Adam Shlien is Associate Director of Translational Genetics in the Department of Paediatric Laboratory Medicine at the Hospital for Sick Children, and a Scientist in the Genetics and Genome Biology division at the SickKids Research Institute. His research team uses the tools of modern sequence-based genomics to discover the mutations that are present in the genomes of paediatric cancer patients, and to understand how these mutations alter the somatic transcriptome. Adam is also directly involved with the introduction of genomics, such as whole genome sequencing, into clinical practice. He co-directs the SickKids Cancer Sequencing program, KiCS, and is on the executive team of Canada’s national precision medicine program for kids and young adults with cancer, PROFYLE. Adam received his PhD from the University of Toronto for the study of copy number variation and cancer susceptibility. He continued his training as a Postdoctoral and Holmes Fellow at the Wellcome Trust Sanger Institute with Sir Mike Stratton and Dr. Peter Campbell, where he developed methods to understand the transcriptional consequences of point mutation in cancer.