AMP Global - Zehir

Ahmet Zehir, PhD

Is currently the Director of Clinical Bioinformatics and Assistant Attending Bioinformatician in the Molecular Diagnostics Service in the Department of Pathology at Memorial Sloan Kettering Cancer Center (MSKCC). He leads a large team of computational biologists and software engineers. He is responsible from overseeing development of Next-Generation Sequencing (NGS) data analysis pipelines and clinical validation of NGS assays. Additionally, he trains clinical bioinformatics analysts and molecular pathology fellows in computational methods for analyzing sequencing data and reviewing pipeline results. He played a major role in developing the analysis pipeline for MSK-IMPACT assay and obtaining NYS-DOH approval as well as FDA authorization. His team also develops software solutions for the molecular laboratory which helps with automated data analysis of test results, automatic report generation and sharing the reports within the hospital systems with the clinicians and researchers. He and his colleagues have also implemented MSI-sensor analysis for a wide variety of tumor types and assessment of tumor mutational burden for solid tumors. His current research interests are focused on two main areas: discovery and characterization of clonal hematopoiesis in patients with advanced disease; discovery of genetic biomarkers related to cancer initiation and progression He is also in charge of advancing new technology to improve the NGS data analysis results and expanding the landscape of NGS results.

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